CU defensive line vs. ASU offensive line
The Buffs have played well up front this year, but this might be their toughest challenge yet. ASU will be intent on running the ball with Eno Benjamin, and CU has to be stout in the trenches.
CU offensive line vs. ASU defensive line
As important as it is to stop the run, the Buffs have to find a way to run the ball. ASU has struggled against the run in the past two weeks. The last time the Buffs played a solid defensive line (Nebraska) they couldn't run. They'll need to get it done this time around.
CU receiver Laviska Shenault vs. ASU secondary
Shenault has dominated everybody the Buffs have played to this point. ASU will have its hands full with the nation's leading receiver.
CU cornerbacks vs. ASU receiver N'Keal Harry
The Sun Devils' top receiver is going to catch some passes, but, as CU coach Mike MacIntyre pointed out this week, the Buffs have to be able to tackle him at the point of the catch and not let him get loose.
CU QB Steven Montez vs. ASU's defense
Colorado's junior quarterback leads the country in completion percentage and has played well all season. The Sun Devils are an active defense that will Montez's pre-snap reads and ability to be accurate and make smart decisions.