Isaac Miller has the size, talent and ability to be one of the top offensive linemen in the Pac-12 Conference.
His right knee just won't allow him to get there.
Colorado head coach Mike MacIntyre said Wednesday that Miller is planning to medically retire from football and focus on his academic future.
"Isaac is not going to play anymore," MacIntyre said. "He's going to go ahead and graduate and go into medical school."
A 6-foot-7 tackle that would have been a redshirt junior next season, Miller graduated from Silver Creek High School in 2014 and has shown great potential during his three seasons with the Buffaloes. Health, however, has been his biggest hurdle.
He had a great spring in 2016, but injured his right knee during the spring game. It was believed to be an MCL sprain, but he ultimately developed tracking issues in his knee cap.
Miller wound up missing the entire 2016 season and then was on and off the field last year. He started four games at right tackle, playing 390 snaps overall.
After Miller missed the entire spring this year, MacIntyre said he for sure would not play in 2018, while leaving the door open for the future.
It appears Miller is ready to close that door.
"He's been trying to (recover)," MacIntyre said. "The doctors and everybody met with him and he kept working on it and it just kept bothering him and bothering him. He wants to still play, but as far as it goes right now, he's not going to be able to do that. He's going to have another surgery on his knee.
"He felt like (football) was just too much to keep trying to do, so I completely agreed with him and wished him the best. He's a phenomenal young man and he'll be successful. Of course we wish he could still play, and so does he, but it just didn't work out that way."
Majoring in integrative physiology and psychology at CU, Miller is excelling in the classroom and on track to graduate with his bachelor's degree in May.
A standout at Silver Creek, Miller helped the Raptors reach three consecutive Class 3A state title games, from 2011-13, winning the championship in 2012. He was also on the Silver Creek honor roll all four years.
Losing Miller puts CU at 84 projected scholarship players for the fall, one below the NCAA maximum of 85.