Offensive lineman Tim Lynott Jr. and safety Ryan Moeller both went down with what appeared to be leg injuries in CU's 41-30 loss to Arizona State, and head coach Mike MacIntyre feared the worst.
"It doesn't look good for either one of them right now," MacIntyre said after the game, "but, we'll find out more (Sunday)."
MacIntyre did not give specifics on either injury, but when asked if he thought either would play the rest of the year, he said, "I don't think so from what I'm hearing, but you never know. I'll be praying tonight. Miracles happen. Hopefully they'll be OK but I don't know."
Lynott and Moeller will be evaluated on Sunday after the Buffs return home from the trip.
A redshirt sophomore, Lynott has started each of CU's 24 games over the past two seasons, with 20 of those starts coming at right guard.
On Saturday, Lynott started his second straight game (and fourth of the season) at center, as senior Jonathan Huckins has dealt with a few injuries. Huckins was cleared this past week and replaced Lynott on Saturday.
Lynott was injured during the second quarter, while Moeller went down in the third.
A senior former walk-on, Moeller made his 27th career start on Saturday, including all 10 games this season.
"Any time you see a guy goes down it hurts you emotionally, it doesn't matter who it is," MacIntyre said.
The Buffs were already playing without junior cornerback Isaiah Oliver, who missed his second game in a row with a leg injury. Oliver, who grew up in nearby Goodyear, Ariz., made the trip but couldn't go in warm-ups.
Reserve defensive lineman Timothy Coleman also missed his second game in a row with a leg injury.
Contact staff writer Brian Howell at firstname.lastname@example.org or twitter.com/BrianHowell33.