With a confident look in her eyes, Chucky Jeffery jumped in the air, let a shot fly and drained it.

Jeffery's first 3-pointer came just 13 seconds into the game on Thursday, but it said a lot about the Colorado junior.

"From that opening shot, she really showed how she was going to play that game," CU coach Linda Lappe said. "She really controlled the game from start to finish, both on the offensive and defensive end."

Led by Jeffery, the Buffs rolled to a 69-59 win over visiting Arizona at Coors Events Center, snapping a three-game losing

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streak. It was also CU's largest margin of victory in conference play.

"It feels great," said Jeffery, who had a game-high 21 points and a career-high five 3-pointers. "I think a lot of our players got a lot of confidence back. We played a full 40 minutes and I think we haven't done that in a long time -- playing defense, getting loose balls and getting on the floor -- things we weren't doing in these past few games.

"We had players step up. It was just an all-around good team win."

The Buffs (16-7, 5-7 Pac-12) clinched a winning record for the second year in a row anddid it with one of their most complete games in Pac-12 play.

CU hit 41.8 percent of its shots, dominating on the boards and, for the first time since beginning the Pac-12 schedule, went into the final minute with a comfortable double-digit lead.

"We earned it," Jeffery said. "Nothing ever comes easy, so it was good to come out and look up and scoreboard and know we've got this sealed. It's a great feeling."

It all started with Jeffery, who had her best offensive output in nearly a month, while also posting six rebounds and five assists.

Brittany Wilson added 12 points and freshman Jasmine Sborov had career-highs in points (10) and rebounds (seven) for the Buffs. The Wildcats (13-11, 2-10) were led by Shanita Arnold and Candice Warthen with 13 points each.

Notoriously slow starters, the Buffs came out firing -- and hitting -- from 3-point range. CU drained its first three shots, including the initial shot from Jeffery, to take a 9-5 lead.

"We're on our home floor and we knew we had to score," said Wilson, who hit two of the first three 3s. "We knew we had to come out and we knew what we had to do to bring the dagger out early."

Arizona got in gear midway through the first half and took a 35-30 lead with 4:49 to go before intermission, taking advantage of CU's lackluster defense. The Wildcats made 63.6 percent of their first-half shots, including 5-of-7 from 3-point range.

"Our defense struggled in the first half, but I thought we made some good changes right before halftime and that led us into the second half," Lappe said.

After Arizona took its five-point lead, CU went on a 15-2 run over the next 7:23.

"That was huge," Lappe said. "We haven't done that for a while, so it was good see us get back to that mentality, that killer-instinct mentality. Then we didn't let them back in and I thought we did a great job. We kept our foot on the gas pedal and stayed focused throughout."

Arizona did pull within 47-45 with 13:30 to go, but a pair of 3s by Jeffery sparked a 12-2 run and the Buffs played the final 10:15 with a double-digit lead.

Coming in with a three-game losing streak, it was exactly what the Buffs needed. But, they feel this one was won in the previous days during practice.

"I think we had an outstanding week in practice," Jeffery said. "We learned to take on that contact and we were going up and getting boards and finishing. Everything translates, and we were extremely focused this week, without a doubt. Forty minutes we were focused the entire time."